The development of 3D organoids as in vitro experimental platform 3D organoids derive from different epithelial cell populations of the adult lung and iPSCs and impact the traditional system of primary culture. Some of the potential future uses of organoids include human disease modeling and gene editing. For example, airway epithelial cells on organoids could be used for observing the biological change under diseases, such as asthma or genetic disease. Organoids could also provide a reliable and reproducible source of human mutant cells by using CRISPR technology, which would overcome...